1
Department of Physical Medicine and Rehabilitation, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
2
Department of Physical Medicine and Rehabilitation, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3
Department of Physical Medicine and Rehabilitation, Isfahan University of Medical Sciences, Isfahan, Iran.
10.30491/tm.2026.595976.1980
Abstract
Introduction: This study aimed to determine and compare the efficacy of two mesotherapy protocols for improving clinical symptoms in patients with trigger points in the upper trapezius muscle. Method: This randomized, open-label clinical trial was conducted in 2026. The 62 participants were randomly assigned to Group A and Group B (n=31 each). Clinical assessments occurred at four time points: baseline, immediately post-treatment, one-month post-treatment, and three months’ post-treatment. Data were collected using a checklist covering demographic information and standardized clinical scales, specifically the Shoulder Pain and Disability Index and McGill Pain Questionnaire. Result: The results showed that piroxicam and lidocaine reduced pain frequency to a mild level (OR 1.43), whereas lidocaine monotherapy yielded an OR of 1.0. Additionally, the combination therapy reduced pain persistence, with an OR of 2.13, compared with an OR of 1.1 for lidocaine alone. Age >47 years and female gender were also identified as predictors of pain reduction. In the piroxicam-lidocaine group, these yielded ORs of 1.89 and 1.12, respectively, compared with 1.31 and 1.0 in the lidocaine group. Conclusion:The combination of lidocaine and piroxicam provides superior short-term pain relief and functional improvement immediately post-treatment.
Taheri, P., Mardanshahi, M., Vahdatpour, B. & Mokhtari, A. (2026). Mesotherapy for Upper Trapezius Myofascial Pain Syndrome: Lidocaine Versus Lidocaine and Piroxicam. Trauma Monthly, 31(5), 2090–2096. https://doi.org/10.30491/tm.2026.595976.1980
MLA
Taheri, P., Mardanshahi, M., Vahdatpour, B., & Mokhtari, A. "Mesotherapy for Upper Trapezius Myofascial Pain Syndrome: Lidocaine Versus Lidocaine and Piroxicam", Trauma Monthly, 31, 5, 2026, 2090–2096. doi: 10.30491/tm.2026.595976.1980
HARVARD
Taheri, P., Mardanshahi, M., Vahdatpour, B., & Mokhtari, A. (2026). 'Mesotherapy for Upper Trapezius Myofascial Pain Syndrome: Lidocaine Versus Lidocaine and Piroxicam', Trauma Monthly, 31(5), pp. 2090–2096. doi: 10.30491/tm.2026.595976.1980
CHICAGO
Taheri, P., Mardanshahi, M., Vahdatpour, B. & Mokhtari, A., "Mesotherapy for Upper Trapezius Myofascial Pain Syndrome: Lidocaine Versus Lidocaine and Piroxicam." Trauma Monthly, 31 5 (2026): 2090–2096, doi: 10.30491/tm.2026.595976.1980
VANCOUVER
Taheri P., Mardanshahi M., Vahdatpour B., Mokhtari A. Mesotherapy for Upper Trapezius Myofascial Pain Syndrome: Lidocaine Versus Lidocaine and Piroxicam. Trauma Mon. 2026;31(5):2090–2096. doi: 10.30491/tm.2026.595976.1980
