Document Type : Original Article
Orthopedic Research Center, Mazandaran University of Medical Sciences, Sari, Iran
Department of Community Medicine, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Department of Internal Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Background: Distal radius fracture (DRF) is one of the most common upper limb fractures, which is associated with osteoporosis and vitamin D deficiency, especially in old adults.
Objectives: The aimof this studywas to evaluate the effectof supplementary vitaminDongrip strength, pinchpower, painintensity, and DASH score in post-menopausal females after distal radius fractures.
Methods: Fifty-two post-menopausal women with distal radius fractures were enrolled in a randomized single-blinded multicenter trial from January 2015 to January 2016 (IRCT registration number: IRCT20160830029603N7). Patients with pre-operative serum vitamin D level of 30 to 100 ng/mL were enrolled in the study. Patients were divided into two randomized groups including groups with and without supplementation of vitamin D [25 women in intervention group (50,000 IU supplementary vitamin D, every 4 weeks for 6 months) and 27 women in placebo group]. Grip strength, pinch power, pain intensity, and DASH score pre-operatively and at three and six months after the surgery were measured; the obtained data were analyzed using SPSS version 16.
Results: The subjects’ mean age in vitamin D supplemented and placebo group was 57.98 ± 7.15 and 59.15 ± 8.03, respectively. The mean grip strength of patients in vitamin D supplemented group was significantly higher than the placebo group on both the third and sixth months (P = 0.011 and P = 0.003, respectively). The pinch power was significantly increased on the sixth month compared to the third month in patients with revised vitamin D supplementation (1.32 ± 2.14 and 0.67 ± 0.96 respectively, P = 0.0001). There was no statistically significant difference between the two groups in terms of mean VAS and DASH scores at the end of the study (P = 241, P = 0.665, respectively).
Conclusions: Vitamin D supplementation was significantly helpful in improving grip strength recovery in post-menopausal women after distal radius fracture, however, no significant differences were observed in supplementation of vitamin D on pinchpower and pain intensity after distal radius fractures.